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Article

Phenotypic analysis of conditionally immortalized cells isolated from the BPK model of ARPKD.

American journal of physiology. Cell physiology - 1 Nov 2001

Sweeney W E, Kusner L, Carlin C R, Chang S, Futey L, Cotton C U, Dell K M, Avner E D

Abstract excerpt

To study the pathophysiology of autosomal recessive polycystic kidney disease (ARPKD), we sought to develop conditionally immortalized control and cystic murine collecting tubule (CT) cell lines. CT cells were isolated from intercross breedings between BPK mice (bpk(+/-)), a murine model of ARPKD, and the Immorto mice (H-2K(b)-ts-A58(+/+)). Second-generation outbred offspring (BPK x Immorto) homozygous for the...

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Identifiers

PMID: 11600434
DOI: 10.1152/ajpcell.2001.281.5.C1695

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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