Article
Impaired tubulogenesis of cyst-derived cells from autosomal dominant polycystic kidneys.
Kidney international - 1 Mar 1995
Carone F A, Nakamura S, Bacallao R, Nelson W J, Khokha M, Kanwar Y S
Abstract excerpt
Under appropriate growth factor or hormonal influence, renal epithelial cells cultured in collagen gels form branching tubular elements, reminiscent of metanephric tubulogenesis. This study evaluates the phenotypic characteristics of normal human renal epithelial cells (NK) and epithelial cells from cysts of autosomal dominant polycystic kidneys (ADPKD) grown in collagen gels under the influence of the growth...
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