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Article

Characterization and chromosomal mapping of two pseudogenes of the mouse Pafaha/Lis1 gene: retrointegration hotspots in the mouse genome.

Gene - 31 Aug 1998

Péterfy M, Gyuris T, Antonio L, Takács L

Abstract excerpt

Isolated lissencephaly sequence and Miller-Dieker syndrome are related neurodevelopmental disorders caused by defects of the LIS1 gene encoding the alpha subunit of intracellular platelet-activating factor acetylhydrolase. In addition to the ortholog of the human LIS1 gene (Pafaha/Lis1), the mouse genome contains two more homologs. In order to characterize the new members of this gene family, we isolated both...

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Source

Identifiers

PMID: 9729401
DOI: 10.1016/s0378-1119(98)00321-7

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