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Article

Fine linkage and physical mapping suggests cross-over suppression with a retroposon insertion at the npc1 mutation.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Sept 2000

Hsu S J, Erickson R P, Zhang J, Garver W S, Heidenreich R A

Abstract excerpt

Mouse Niemann-Pick disease type C1 (npc1), formerly designated spm (sphingomyelinosis), is an autosomal recessive lipid storage disorder. We generated a high-resolution linkage map in the 2.24-cM npc1 critical region by typing eight polymorphic markers in 2322 meioses (948 of these were previously reported). A minimal set of overlapping yeast artificial chromosomes (YACs) had previously been assembled (Hsu and...

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PMID: 10967137
DOI: 10.1007/s003350010134

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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