Article
High frequency de novo alterations in the long-range genomic structure of the mouse pseudoautosomal region.
Nature genetics - 1 May 1996
Kipling D, Salido E C, Shapiro L J, Cooke H J
Abstract excerpt
The pseudoautosomal region (PAR) is a segment of shared homology between the X and Y chromosomes. Here we report physical linkage of three mouse PAR probes: DXYHgu1, DXYMov15 and (TTAGGG)n. Steroid sulphatase (Sts) maps distal to these probes, indicating that there is an internal array of the telomere sequence (TTAGGG)n in the PAR. Pseudoautosomal PacI restriction fragments, up to 2 Mb in size, are unstable in...
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