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Article

Polymorphic imprinting of the serotonin-2A (5-HT2A) receptor gene in human adult brain.

Brain research. Molecular brain research - 15 Aug 1998

Bunzel R, Blümcke I, Cichon S, Normann S, Schramm J, Propping P, Nöthen M M

Abstract excerpt

We have examined the imprinting status of the serotonin-2A (5-HT2A) receptor gene (HTR2A) in a series of 41 tissue samples from human adult brain. Using a HpaII RFLP polymorphism in the coding region, we obtained evidence of monoallelic expression of HTR2A in 4 out of 18 informative individuals. However, biallelic expression of HTR2A was observed in other individuals (14/18), suggesting that within the human...

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PMID: 9729300
DOI: 10.1016/s0169-328x(98)00146-6

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