Article
Polymorphic imprinting of the serotonin-2A (5-HT2A) receptor gene in human adult brain.
Brain research. Molecular brain research - 15 Aug 1998
Bunzel R, Blümcke I, Cichon S, Normann S, Schramm J, Propping P, Nöthen M M
Abstract excerpt
We have examined the imprinting status of the serotonin-2A (5-HT2A) receptor gene (HTR2A) in a series of 41 tissue samples from human adult brain. Using a HpaII RFLP polymorphism in the coding region, we obtained evidence of monoallelic expression of HTR2A in 4 out of 18 informative individuals....
Topics
- Alleles
- Brain
- Genomic Imprinting
- Humans
- Polymerase Chain Reaction
- Polymorphism, Genetic
- Receptor, Serotonin, 5-HT2A
- Receptors, Serotonin
