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Article

UNC-115, a conserved protein with predicted LIM and actin-binding domains, mediates axon guidance in C. elegans.

Neuron - 1 Aug 1998

Lundquist E A, Herman R K, Shaw J E, Bargmann C I

Abstract excerpt

Axon guidance receptors modulate the growth cone cytoskeleton through signaling pathways that are not well understood. Here, we describe the C. elegans unc-115 gene, which encodes a candidate cytoskeletal linker protein that acts in axon guidance. unc-115 mutants have defects in a subset of axons, particularly as the affected axons change environments during outgrowth. The unc-115 gene encodes a putative...

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PMID: 9728919
DOI: 10.1016/s0896-6273(00)80547-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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UNC-115, a conserved protein with predicted LIM and actin-binding domains, mediates axon guidance in C. elegans.PMID 9728919Read ↗

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