Article
Introduction of the IBD information into the weighted pairwise correlation method for linkage analysis.
Genetic epidemiology - 1 Jan 1999
Zinn-Justin A, Abel L
Abstract excerpt
The Weighted Pairwise Correlation (WPC) approach is a non-parametric method of linkage analysis that allows analysis of any kind of phenotypes (quantitative, binary, binary with age of onset) and to consider all pairs of relatives in a pedigree. The principle of this method is to test whether two relatives having close phenotypes also resemble at the marker locus more than expected under the null hypothesis of no...
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