Heterogeneity of microsatellite mutations within and between loci, and implications for human demographic histories.

doi:10.1093/genetics/148.3.1269

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Article

Heterogeneity of microsatellite mutations within and between loci, and implications for human demographic histories.

Genetics - 1 Mar 1998

Di Rienzo A, Donnelly P, Toomajian C, Sisk B, Hill A, Petzl-Erler M L, Haines G K, Barch D H

Abstract excerpt

Microsatellites have been widely used to reconstruct human evolution. However, the efficient use of these markers relies on information regarding the process producing the observed variation. Here, we present a novel approach to the locus-by-locus characterization of this process. By analyzing so...

Topics

Adenocarcinoma
Colonic Neoplasms
DNA, Satellite
Discriminant Analysis
Genetic Heterogeneity
Genetic Testing
Humans
Microsatellite Repeats
Models, Genetic
Mutation
Population

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