Article
Biased mutations and microsatellite variation.
Molecular biology and evolution - 1 Sept 1997
Zhivotovsky L A, Feldman M W, Grishechkin S A
Abstract excerpt
Mutation bias is one of the forces that may constrain the variation at microsatellite loci. Here, we study the dynamics of population statistics and the genetic distance between two populations under multiple stepwise mutations with linear bias and random drift. Expressions are derived for these statistics as functions of time, as well as at mutation-drift equilibrium. Applying these expressions to published data...
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