Article
CTL response to Mycobacterium tuberculosis: identification of an immunogenic epitope in the 19-kDa lipoprotein.
Journal of immunology (Baltimore, Md. : 1950) - 1 Sept 1998
Mohagheghpour N, Gammon D, Kawamura L M, van Vollenhoven A, Benike C J, Engleman E G
Abstract excerpt
The successful resolution of infection with Mycobacterium tuberculosis (M.tb) is believed to involve the induction of CTLs that are capable of killing cells harboring this pathogen, although little information is known about the MHC restriction or fine specificity of such CTLs. In this study, we used knowledge of the HLA-A*0201-binding motif and an immunofluorescence-based peptide-binding assay to screen for...
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