Article
CTL response to Mycobacterium tuberculosis: identification of an immunogenic epitope in the 19-kDa lipoprotein.
Journal of immunology (Baltimore, Md. : 1950) - 1 Sept 1998
Mohagheghpour N, Gammon D, Kawamura L M, van Vollenhoven A, Benike C J, Engleman E G
Abstract excerpt
The successful resolution of infection with Mycobacterium tuberculosis (M.tb) is believed to involve the induction of CTLs that are capable of killing cells harboring this pathogen, although little information is known about the MHC restriction or fine specificity of such CTLs. In this study, we...
Topics
- Alleles
- Bacterial Proteins
- Cytotoxicity, Immunologic
- Epitopes, T-Lymphocyte
- HLA-A Antigens
- Humans
- Immunodominant Epitopes
- Lipoproteins
- Lymphocyte Activation
- Molecular Weight
- Mycobacterium tuberculosis
- Peptide Fragments
- Protein Binding
- T-Lymphocytes, Cytotoxic