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Article

Induction of a type 1 immune response to a recombinant antigen from Mycobacterium tuberculosis expressed in Mycobacterium vaccae.

Infection and immunity - 1 May 1997

Abou-Zeid C, Gares M P, Inwald J, Janssen R, Zhang Y, Young D B, Hetzel C, Lamb J R, Baldwin S L, Orme I M, Yeremeev V, Nikonenko B V, Apt A S

Abstract excerpt

A 19-kDa lipoprotein from Mycobacterium tuberculosis was expressed as a recombinant antigen in the nonpathogenic mycobacterial host strain M. vaccae. Immunization of mice with the recombinant M. vaccae resulted in induction of a strong type 1 immune response to the 19-kDa antigen, characterized by immunoglobulin G2a (IgG2a) antibodies and gamma interferon (IFN-gamma) production by splenocytes. Immunization with...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Electrophoresis, Polyacrylamide Gel

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Source

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Identifiers

PMID: 9125572
DOI: 10.1128/iai.65.5.1856-1862.1997
PMCID: PMC175231

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Source receipt: pubmed, retrieved 7 Sept 2026.

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