Article
Epitope specificity and isoforms of the mycobacterial 19-kilodalton antigen.
Infection and immunity - 1 Jul 1994
Harris D P, Vordermeier H M, Brett S J, Pasvol G, Moreno C, Ivanyi J
Abstract excerpt
The topography and specificity of B- and T-cell stimulatory epitopes from the 19-kDa protein of Mycobacterium tuberculosis were investigated by using overlapping synthetic peptides. Murine antisera identified two cryptic epitopes (residues 11 to 30 and 61 to 80) and one species-specific immunodom...
Topics
- Amino Acid Sequence
- Animals
- Antibodies, Bacterial
- Antibody Specificity
- B-Lymphocytes
- Bacterial Proteins
- Cross Reactions
- Cytokines
- Epitopes
- Genetic Variation
- H-2 Antigens
- Humans
