Article
TAFII105 mediates activation of anti-apoptotic genes by NF-kappaB.
The EMBO journal - 1 Sept 1998
Yamit-Hezi A, Dikstein R
Abstract excerpt
The transcription factor NF-kappaB is important for expression of genes involved in immune responses, viral infections, cytokine signaling and stress. In addition NF-kappaB plays a crucial role in protecting cells from TNF-alpha-induced apoptotic stimuli, presumably by activating anti-apoptotic genes. Here we report that the sub-stoichiometric TFIID subunit TAFII105 is essential for activation of anti-apoptotic...
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