Article
Identification of a ZU5 and death domain-containing inhibitor of NF-kappaB.
The Journal of biological chemistry - 23 Apr 2004
Zhang Jun, Xu Liang-Guo, Han Ke-Jun, Shu Hong-Bing
Abstract excerpt
The transcription factor NF-kappaB plays important roles in inflammation and cell survival. NF-kappaB is composed of homodimeric and heterodimeric complexes of Rel/NF-kappaB family members, including p65 (RelA), c-Rel (Rel), RelB, NF-kappaB1/p50, and NF-kappaB2/p52. Here we report the identification and characterization of a novel ZU5 and death domain-containing protein designated ZUD. In reporter gene assays,...
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