Article
Human TAF(II)135 potentiates transcriptional activation by the AF-2s of the retinoic acid, vitamin D3, and thyroid hormone receptors in mammalian cells.
Genes & development - 1 Jun 1997
Mengus G, May M, Carré L, Chambon P, Davidson I
Abstract excerpt
We report for the first time the cloning of a complete cDNA encoding the human TFIID subunit hTAF(II)135 (hTAF(II)130). Full-length hTAF(II)135 comprises 1083 amino acids and contains two conserved domains present also in dTAF(II)110 and hTAF(II)105. We show that expression of hTAF(II)135 in mamm...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- COS Cells
- Cell Line
- Cloning, Molecular
- DNA-Binding Proteins
- Genes, Reporter
- HeLa Cells
- Humans
- Molecular Sequence Data
- Mutation
- Receptors, Calcitriol
- Receptors, Retinoic Acid
- Receptors, Thyroid Hormone
- Recombinant Proteins
- Sequence Analysis, DNA
- Sequence Deletion