Article
Novel sites in the p65 subunit of NF-kappaB interact with TFIIB to facilitate NF-kappaB induced transcription.
FEBS letters - 12 Mar 2004
Xia Chulin, Watton Sandra, Nagl Sylvia, Samuel Jane, Lovegrove Jenny, Cheshire John, Woo Patricia
Abstract excerpt
Nuclear factor kappaB (NF-kappaB) transcription factors regulate a large number of genes in response to inflammation, infection and stressful conditions. In this study, we investigated whether NF-kappaB p65 regulates the transcription of target genes by interacting with components of the basal transcription machinery. We examined the interaction of p65 with the basal transcription factor IIB (TFIIB). Glutathione...
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