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Article

Nip1p associates with 40 S ribosomes and the Prt1p subunit of eukaryotic initiation factor 3 and is required for efficient translation initiation.

The Journal of biological chemistry - 4 Sept 1998

Greenberg J R, Phan L, Gu Z, deSilva A, Apolito C, Sherman F, Hinnebusch A G, Goldfarb D S

Abstract excerpt

Nip1p is an essential Saccharomyces cerevisiae protein that was identified in a screen for temperature conditional (ts) mutants exhibiting defects in nuclear transport. New results indicate that Nip1p has a primary role in translation initiation. Polysome profiles indicate that cells depleted of Nip1p and nip1-1 cells are defective in translation initiation, a conclusion that is supported by a reduced rate of...

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Source

Identifiers

PMID: 9722586
DOI: 10.1074/jbc.273.36.23485

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Nip1p associates with 40 S ribosomes and the Prt1p subunit of eukaryotic initiation factor 3 and is required for efficient translation initiation.PMID 9722586Read ↗

Saccharomyces cerevisiae Nip7p is required for efficient 60S ribosome subunit biogenesis.Semantic proximity Read ↗

Nip7p interacts with Nop8p, an essential nucleolar protein required for 60S ribosome biogenesis, and the exosome subunit Rrp43p.Semantic proximity Read ↗

Enp1, a yeast protein associated with U3 and U14 snoRNAs, is required for pre-rRNA processing and 40S subunit synthesis.Semantic proximity Read ↗

The shuttling protein Npl3 promotes translation termination accuracy in Saccharomyces cerevisiae.Semantic proximity Read ↗

NIP1, a gene required for nuclear transport in yeast.Semantic proximity Read ↗

NSR1 is required for pre-rRNA processing and for the proper maintenance of steady-state levels of ribosomal subunits.Semantic proximity Read ↗

Ria1p (Ynl163c), a protein similar to elongation factors 2, is involved in the biogenesis of the 60S subunit of the ribosome in Saccharomyces cerevisiae.Semantic proximity Read ↗

Intersection of the Kap123p-mediated nuclear import and ribosome export pathways.Semantic proximity Read ↗

Mutational analysis of the Prt1 protein subunit of yeast translation initiation factor 3.Semantic proximity Read ↗

The mitochondrial protein targeting suppressor (mts1) mutation maps to the mRNA-binding domain of Npl3p and affects translation on cytoplasmic polysomes.Semantic proximity Read ↗

Ebp2p, yeast homologue of a human protein that interacts with Epstein-Barr virus nuclear antigen 1, is required for pre-rRNA processing and ribosomal subunit assembly.Semantic proximity Read ↗

Target of rapamycin complex 1 and Tap42-associated phosphatases are required for sensing changes in nitrogen conditions in the yeast Saccharomyces cerevisiae.Semantic proximity Read ↗

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