Article
Nip1p associates with 40 S ribosomes and the Prt1p subunit of eukaryotic initiation factor 3 and is required for efficient translation initiation.
The Journal of biological chemistry - 4 Sept 1998
Greenberg J R, Phan L, Gu Z, deSilva A, Apolito C, Sherman F, Hinnebusch A G, Goldfarb D S
Abstract excerpt
Nip1p is an essential Saccharomyces cerevisiae protein that was identified in a screen for temperature conditional (ts) mutants exhibiting defects in nuclear transport. New results indicate that Nip1p has a primary role in translation initiation. Polysome profiles indicate that cells depleted of...
Topics
- Cell Division
- Eukaryotic Initiation Factor-3
- Fungal Proteins
- Mutation
- Nuclear Proteins
- Paromomycin
- Peptide Chain Initiation, Translational
- Peptide Initiation Factors
- Polyribosomes
- Protein Binding
- Ribosomal Proteins
- Ribosomes
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins