Article
Saccharomyces cerevisiae Nip7p is required for efficient 60S ribosome subunit biogenesis.
Molecular and cellular biology - 1 Sept 1997
Zanchin N I, Roberts P, DeSilva A, Sherman F, Goldfarb D S
Abstract excerpt
The Saccharomyces cerevisiae temperature-sensitive (ts) allele nip7-1 exhibits phenotypes associated with defects in the translation apparatus, including hypersensitivity to paromomycin and accumulation of halfmer polysomes. The cloned NIP7+ gene complemented the nip7-1 ts growth defect, the paromomycin hypersensitivity, and the halfmer defect. NIP7 encodes a 181-amino-acid protein (21 kDa) with homology to...
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