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Article

NIP1, a gene required for nuclear transport in yeast.

Proceedings of the National Academy of Sciences of the United States of America - 1 Nov 1992

Gu Z, Moerschell R P, Sherman F, Goldfarb D S

Abstract excerpt

Cytochrome c with a nuclear localization signal added at the N terminus was mistargeted to the nucleus, resulting in a yeast strain deficient in mitochondrial cytochrome c. Reversion of this strain allowed the isolation of temperature-conditional mutants defective in nuclear transport, as demonstrated with one of these mutants, nip1-1, that was shown to be defective in nuclear accumulation of a LacZ protein...

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PMID: 1332047
DOI: 10.1073/pnas.89.21.10355
PMCID: PMC50337

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