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Article

Enp1, a yeast protein associated with U3 and U14 snoRNAs, is required for pre-rRNA processing and 40S subunit synthesis.

Nucleic acids research - 15 Jan 2003

Chen Weidong, Bucaria Jean, Band David A, Sutton Ann, Sternglanz Rolf

Abstract excerpt

ENP1 is an essential Saccharomyces cerevisiae gene encoding a 483 amino acid polypeptide. Enp1 protein is localized in the nucleus and concentrated in the nucleolus. An enp1-1 temperature-sensitive mutant inhibited 35S pre-rRNA early processing at sites A(0), A(1) and A(2) as shown by northern analysis of steady state levels of rRNA precursors. Pulse-chase analysis further revealed that the enp1-1 strain was...

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Identifiers

PMID: 12527778
DOI: 10.1093/nar/gkg145
PMCID: PMC140510

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Source receipt: pubmed, retrieved 7 Sept 2026.

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