Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

NSR1 is required for pre-rRNA processing and for the proper maintenance of steady-state levels of ribosomal subunits.

Molecular and cellular biology - 1 Sept 1992

Lee W C, Zabetakis D, Mélèse T

Abstract excerpt

NSR1 is a yeast nuclear localization sequence-binding protein showing striking similarity in its domain structure to nucleolin. Cells lacking NSR1 are viable but have a severe growth defect. We show here that NSR1, like nucleolin, is involved in ribosome biogenesis. The nsr1 mutant is deficient in pre-rRNA processing such that the initial 35S pre-rRNA processing is blocked and 20S pre-rRNA is nearly absent. The...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Fungal Proteins
Share to Mutation
Share to Nuclear Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Ribosomes

Share to RNA-Binding Proteins

Share to RNA, Ribosomal

Share to Saccharomyces cerevisiae

Share to Saccharomyces cerevisiae Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 1508189
DOI: 10.1128/mcb.12.9.3865-3871.1992
PMCID: PMC360260

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

NSR1 is required for pre-rRNA processing and for the proper maintenance of steady-state levels of ribosomal subunits.PMID 1508189Read ↗

Enp1, a yeast protein associated with U3 and U14 snoRNAs, is required for pre-rRNA processing and 40S subunit synthesis.Semantic proximity Read ↗

Nop6, a component of 90S pre-ribosomal particles, is required for 40S ribosomal subunit biogenesis in Saccharomyces cerevisiae.Semantic proximity Read ↗

Saccharomyces cerevisiae nucleolar protein Nop7p is necessary for biogenesis of 60S ribosomal subunits.Semantic proximity Read ↗

rRNA maturation in yeast cells depleted of large ribosomal subunit proteins.Semantic proximity Read ↗

Rrs1p, a ribosomal protein L11-binding protein, is required for nuclear export of the 60S pre-ribosomal subunit in Saccharomyces cerevisiae.Semantic proximity Read ↗

The putative GTPases Nog1p and Lsg1p are required for 60S ribosomal subunit biogenesis and are localized to the nucleus and cytoplasm, respectively.Semantic proximity Read ↗

The path from nucleolar 90S to cytoplasmic 40S pre-ribosomes.Semantic proximity Read ↗

Rrb1p, a yeast nuclear WD-repeat protein involved in the regulation of ribosome biosynthesis.Semantic proximity Read ↗

Ribosomal protein L35 is required for 27SB pre-rRNA processing in Saccharomyces cerevisiae.Semantic proximity Read ↗

Nsa2 is an unstable, conserved factor required for the maturation of 27 SB pre-rRNAs.Semantic proximity Read ↗

Normal assembly of 60 S ribosomal subunits is required for the signaling in response to a secretory defect in Saccharomyces cerevisiae.Semantic proximity Read ↗

Nucleolar protein Nop12p participates in synthesis of 25S rRNA in Saccharomyces cerevisiae.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.