Article
Target of rapamycin complex 1 and Tap42-associated phosphatases are required for sensing changes in nitrogen conditions in the yeast Saccharomyces cerevisiae.
Molecular microbiology - 1 Dec 2017
Li Jinmei, Yan Gonghong, Liu Sichi, Jiang Tong, Zhong Mingming, Yuan Wenjie, Chen Shaoxian, Zheng Yin, Jiang Yong, Jiang Yu
Abstract excerpt
In yeast target of rapamycin complex 1 (TORC1) and Tap42-associated phosphatases regulate expression of genes involved in nitrogen limitation response and the nitrogen discrimination pathway. However, it remains unclear whether TORC1 and the phosphatases are required for sensing nitrogen conditions. Utilizing temperature sensitive mutants of tor2 and tap42, we examined the role of TORC1 and Tap42 in nuclear entry...
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