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Article

Modulation of human CACO-2 intestinal epithelial cell phenotype by protein kinase C inhibitors.

Cell biology international - 1 Dec 1995

Basson M D, Hong F

Abstract excerpt

Protein kinase C (PKC) isoforms are altered in colon tumors and upon exposure of intestinal mucosa to nutrients. We evaluated the effects of the PKC inhibitors staurosporine and calphostin C on human Caco-2 intestinal epithelial proliferation, motility, and differentiation. Motility was quantitated by monolayer expansion and the brush border enzymes dipeptidyl dipeptidase (DPDD) and alkaline phosphatase (AP) by...

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Identifiers

PMID: 9721628
DOI: 10.1006/cbir.1995.1045

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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