Article
Evolution of the major pilus gene cluster of Haemophilus influenzae.
Journal of bacteriology - 1 Sept 1998
Mhlanga-Mutangadura T, Morlin G, Smith A L, Eisenstark A, Golomb M
Abstract excerpt
Haemophilus influenzae is a ubiquitous colonizer of the human respiratory tract and causes diseases ranging from otitis media to meningitis. Many H. influenzae isolates express pili (fimbriae), which mediate adherence to epithelial cells and facilitate colonization. The pilus gene (hif) cluster of H. influenzae type b maps between purE and pepN and resembles a pathogenicity island: it is present in invasive...
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