Article
The Widespread Colonization Island of Actinobacillus actinomycetemcomitans.
Nature genetics - 1 Jun 2003
Planet Paul J, Kachlany Scott C, Fine Daniel H, DeSalle Rob, Figurski David H
Abstract excerpt
Genomic islands, such as pathogenicity islands, contribute to the evolution and diversification of microbial life. Here we report on the Widespread Colonization Island, which encompasses the tad (tight adherence) locus for colonization of surfaces and biofilm formation by the human pathogen Actinobacillus actinomycetemcomitans. At least 12 of the 14 genes at the tad locus are required for tenacious biofilm...
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