Article
The fimbrial gene cluster of Haemophilus influenzae type b.
Molecular microbiology - 1 Aug 1994
van Ham S M, van Alphen L, Mooi F R, van Putten J P
Abstract excerpt
Haemophilus influenzae infections are preceded by airway colonization, a process facilitated by fimbriae. Here, we identified the complete fimbrial gene cluster of H. influenzae type b. HifA forms the major subunit. HifB, a periplasmic chaperone, and HifC, an outer membrane usher, are typical assembly genes; their inactivation abolished fimbriae formation. HifD and HifE are putative minor subunits, both...
Topics
- Amino Acid Sequence
- Bacterial Outer Membrane Proteins
- Bacterial Proteins
- Base Sequence
- Escherichia coli
- Fimbriae Proteins
- Fimbriae, Bacterial
- Gene Expression Regulation, Bacterial
- Genes, Bacterial
- Haemophilus influenzae
- Microscopy, Immunoelectron