Article
Genetic evidence for a novel variant of the pilus island 1 backbone protein in group B Streptococcus.
Journal of medical microbiology - 1 Oct 2017
Teatero Sarah, Neemuchwala Alefiya, Yang Kunlin, Gomes Janice, Athey Taryn B T, Martin Irene, Demczuk Walter, McGeer Allison, Fittipaldi Nahuel
Abstract excerpt
PURPOSE: Pili contribute significantly to the pathogenesis of infection of group B Streptococcus (GBS) by facilitating adhesion and invasion of host cells. GBS pilin subunits (the backbone pilin protein, BP, and the ancillary pilin proteins, AP) as well as the specific enzymes required for pilus assembly are encoded by genes located in two separate genomic regions, known as pilus island 1 (PI-1) and PI-2. Our aim...
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