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Article

Identification of genetic loci implicated in the survival of Mycobacterium smegmatis in human mononuclear phagocytes.

Molecular microbiology - 1 Jul 1998

Lagier B, Pelicic V, Lecossier D, Prod'hom G, Rauzier J, Guilhot C, Gicquel B, Hance A J

Abstract excerpt

A luminescence-based procedure that permits the rapid evaluation of the survival of mycobacteria within mononuclear phagocytes was developed and used to screen insertional mutants of Mycobacterium smegmatis for their ability to survive in human monocyte-derived macrophages. Among the 5000 mutants tested, eight mutants were identified that demonstrated impaired intracellular survival in human macrophages but that...

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Source

Identifiers

PMID: 9720865
DOI: 10.1046/j.1365-2958.1998.00933.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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