Article
Noncanonical SMC protein in Mycobacterium smegmatis restricts maintenance of Mycobacterium fortuitum plasmids.
Proceedings of the National Academy of Sciences of the United States of America - 16 Sept 2014
Panas Michael W, Jain Paras, Yang Hui, Mitra Shimontini, Biswas Debasis, Wattam Alice Rebecca, Letvin Norman L, Jacobs William R
Abstract excerpt
Research on tuberculosis and leprosy was revolutionized by the development of a plasmid transformation system in the fast-growing surrogate, Mycobacterium smegmatis. This transformation system was made possible by the successful isolation of a M. smegmatis mutant strain mc(2)155, whose efficient plasmid transformation (ept) phenotype supported the replication of Mycobacterium fortuitum pAL5000 plasmids. In this...
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