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Article

Characterization of a Mycobacterium smegmatis mutant lacking penicillin binding protein 1.

Antimicrobial agents and chemotherapy - 1 Dec 1999

Billman-Jacobe H, Haites R E, Coppel R L

Abstract excerpt

The ponA gene of Mycobacterium smegmatis encodes a 95-kDa penicillin binding protein, PBP1, that is similar to PBP1s of Mycobacterium tuberculosis and Mycobacterium leprae. Transposon disruption of ponA in M. smegmatis resulted in a PBP1-deficient mutant that was sensitive to beta-lactam antibiotics, was more permeable to glycine, and grew slowly in liquid culture.

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Source

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Identifiers

PMID: 10582900
DOI: 10.1128/AAC.43.12.3011
PMCID: PMC89605

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Characterization of a Mycobacterium smegmatis mutant lacking penicillin binding protein 1.PMID 10582900Read ↗

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