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Article

Identification of Legionella pneumophila genes required for growth within and killing of human macrophages.

Infection and immunity - 1 Dec 1993

Sadosky A B, Wiater L A, Shuman H A

Abstract excerpt

Legionella pneumophila was mutagenized with Tn903dIIlacZ, and a collection of mutants was screened for defects in macrophage killing (Mak-). Of 4,564 independently derived mutants, 55 (1.2%) showed a reduced or complete lack in the ability to kill HL-60-derived human macrophages. Forty-nine of the Mak- mutants could be assigned to one of 16 DNA hybridization groups. Only one group (9 of the 10 members) could be...

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Identifiers

PMID: 8225610
DOI: 10.1128/iai.61.12.5361-5373.1993
PMCID: PMC281323

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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