Article
Identification of Mycobacterium marinum macrophage infection mutants.
Microbial pathogenesis - 1 Apr 2006
Mehta Parmod K, Pandey Amit K, Subbian Selvakumar, El-Etr Sahar H, Cirillo Suat L G, Samrakandi Mustapha M, Cirillo Jeffrey D
Abstract excerpt
Mycobacterium marinum is an important pathogen of humans, amphibians and fish. Most pathogenic mycobacteria, including M. marinum, infect, survive and replicate primarily intracellularly within macrophages. We constructed a transposon mutant library in M. marinum using Tn5367 delivered by phage transduction in the shuttle phasmid phAE94. We screened 529 clones from the transposon library directly in macrophage...
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