Distribution of fitness effects caused by random insertion mutations in Escherichia coli.

Article

Distribution of fitness effects caused by random insertion mutations in Escherichia coli.

Genetica - 1 Jan 1998

Elena S F, Ekunwe L, Hajela N, Oden S A, Lenski R E

Abstract excerpt

Very little is known about the distribution of mutational effects on organismal fitness, despite the fundamental importance of this information for the study of evolution. This lack of information reflects the fact that it is generally difficult to quantify the dynamic effects of mutation and nat...

Topics

Biological Evolution
DNA Transposable Elements
Directed Molecular Evolution
Escherichia coli
Genetic Vectors
Genotype
Models, Genetic
Mutagenesis, Insertional
Selection, Genetic

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.