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Article

Methylenetetrahydrofolate reductase gene polymorphism: relation to blood pressure and cerebrovascular disease.

American journal of hypertension - 1 Aug 1998

Nakata Y, Katsuya T, Takami S, Sato N, Fu Y, Ishikawa K, Takiuchi S, Rakugi H, Miki T, Higaki J, Ogihara T

Abstract excerpt

Hyperhomocysteinemia is reported to be associated with an increase in the incidence of ischemic heart disease and cerebrovascular disease. Genetic aberrations in methylenetetrahydrofolate reductase (MTHFR) may account for reduced enzyme activity and elevated plasma homocysteine level. A recent re...

Topics

Cerebrovascular Disorders
Folic Acid
Homocysteine
Humans
Hypertension
Methylenetetrahydrofolate Reductase (NADPH2)
Mutation
Oxidoreductases Acting on CH-NH Group Donors
Polymorphism, Genetic
Risk Factors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 9715796
DOI: 10.1016/s0895-7061(98)00046-6

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9715796-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Methylenetetrahydrofolate reductase gene polymorphism: relation to blood pressure and cerebrovascular disease.PMID 9715796Read ↗

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