C677T and A1298C methylenetetrahydropholate reductase (MTHFR) polymorphisms as factors involved in ischemic stroke.

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Article

C677T and A1298C methylenetetrahydropholate reductase (MTHFR) polymorphisms as factors involved in ischemic stroke.

Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie - 1 Jan 2011

Arsene D, Găină Gisela, Bălescu Carmen, Ardeleanu Carmen

Abstract excerpt

BACKGROUND: Ischemic stroke is a major health problem. Data regarding the possible association between ischemic stroke and the polymorphism of methylenetetrahydropholate reductase (MTHFR) C677T and A1298C are still conflictual. AIM: The study tried to assess the association of the two MTHFR polymorphisms with ischemic stroke in a series of patients from a unique hospital center. MATERIALS AND METHODS: The study...

Topics

Aged
Aged, 80 and over
Brain Ischemia
Female
Genetic Predisposition to Disease
Humans
Male
Methylenetetrahydrofolate Reductase (NADPH2)
Middle Aged
Polymorphism, Single Nucleotide
Staining and Labeling
Stroke

Source

Open in PubMed

Identifiers

PMID: 22203923

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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