Restricted and individual usage of T-cell receptor beta-gene variables in nickel-induced CD4+ and CD8+ cells.

doi:10.1046/j.1365-3083.1998.00367.x

Back to search

Article

Restricted and individual usage of T-cell receptor beta-gene variables in nickel-induced CD4+ and CD8+ cells.

Scandinavian journal of immunology - 1 Jul 1998

Silvennoinen-Kassinen S, Karvonen J, Ikäheimo I

Abstract excerpt

Nickel allergy is manifested as contact allergic eczema elicited by delayed-type hypersensitivity, the reaction being mediated by T lymphocytes. We examined the T-cell receptor (TCR) beta-chain variable gene segment (Vbeta) use of nickel-induced CD4+ and CD8+ T cells in the peripheral blood of ni...

Topics

Adult
CD4-Positive T-Lymphocytes
CD8-Positive T-Lymphocytes
Genetic Variation
Humans
Nickel
Receptors, Antigen, T-Cell, alpha-beta

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.