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Article

Mononuclear cell subsets in the nickel-allergic reaction in vitro and in vivo.

The Journal of allergy and clinical immunology - 1 Apr 1992

Silvennoinen-Kassinen S, Ikäheimo I, Karvonen J, Kauppinen M, Kallioinen M

Abstract excerpt

Nickel is the major cause of metal-induced contact allergy. To understand the mechanism of its immune reaction, we studied changes in lymphocyte surface markers during nickel challenge in both allergic and healthy subjects using an in vitro nickel reaction in which the lymphocytes of allergic sub...

Topics

Antigens, Differentiation
Antigens, Differentiation, T-Lymphocyte
Biopsy
CD3 Complex
CD4 Antigens
Dermatitis, Contact
HLA-DR Antigens
Humans
Leukocytes, Mononuclear
Lymphocyte Activation
Nickel
Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Receptors, Antigen, T-Cell

Receptors, Fc

Receptors, IgG

Receptors, Interleukin-2

Skin

Source

Identifiers

PMID: 1532806
DOI: 10.1016/0091-6749(92)90433-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1532806-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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