No evidence for association of serotonin-2A receptor variant (102T/C) with schizophrenia or clozapine response in a Chinese population.

doi:10.1097/00001756-199901180-00011

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Article

No evidence for association of serotonin-2A receptor variant (102T/C) with schizophrenia or clozapine response in a Chinese population.

Neuroreport - 18 Jan 1999

Lin C H, Tsai S J, Yu Y W, Song H L, Tu P C, Sim C B, Hsu C P, Yang K H, Hong C J

Abstract excerpt

The serotonin hypothesis in schizophrenia had regained interest with the superior efficacy of clozapine in the refractory schizophrenic patients. Among the serotonin receptors, the serotonin 2A (5HT2A) receptor subtype is the most widely studied. Previous studies on the association between a silent mutation polymorphism of the 5HT2A gene (102T/C) and schizophrenia or clozapine response have yielded conflicting...

Topics

Adult
Antipsychotic Agents
Asian People
Clozapine
Female
Humans
Male
Mutation
Polymorphism, Genetic
Receptor, Serotonin, 5-HT2A
Receptors, Serotonin
Schizophrenia
Serotonin Antagonists
Taiwan

Source

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Identifiers

PMID: 10094133
DOI: 10.1097/00001756-199901180-00011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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