Article
A Y chromosomal influence on prostate cancer risk: the multi-ethnic cohort study.
Journal of medical genetics - 1 Nov 2003
Paracchini S, Pearce C L, Kolonel L N, Altshuler D, Henderson B E, Tyler-Smith C
Abstract excerpt
BACKGROUND: A Y chromosomal role in prostate cancer has previously been suggested by both cytogenetic findings and patterns of Y chromosomal gene expression. We took advantage of the well established and stable phylogeny of the non-recombining segment of the Y chromosome to investigate the association between Y chromosomal DNA variation and prostate cancer risk. METHODS: We examined the distribution of 116 Y...
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