Article
A p53 codon 72 polymorphism associated with prostate cancer development and progression in Japanese.
Journal of biomedical science - 1 Jan 2000
Suzuki Kazuhiro, Matsui Hiroshi, Ohtake Nobuaki, Nakata Seiji, Takei Tomoyuki, Nakazato Haruki, Okugi Hironobu, Koike Hidekazu, Ono Yoshihiro, Ito Kazuto, Kurokawa Kohei, Yamanaka Hidetoshi
Abstract excerpt
An association between the Pro/Pro genotype of p53 codon 72 and a lower risk of prostate cancer in Caucasians was recently reported. However, the association of this polymorphism with prostate cancer risk in a Japanese population has not been clarified. We performed a case-control study consisting of 114 prostate cancer patients and 105 noncancer controls. Sixty-nine percent (79 of 114) of the patients had a...
Topics
- Adult
- Aged
- Asian People
- Case-Control Studies
- Codon
- Disease Progression
- Genes, p53
- Genetic Predisposition to Disease
- Genotype
- Humans
- Male
- Middle Aged
- Polymorphism, Genetic