Article
Validation of haplotype frequency estimation methods.
Human immunology - 1 Aug 1998
Schipper R F, D'Amaro J, de Lange P, Schreuder G M, van Rood J J, Oudshoorn M
Abstract excerpt
In order to investigate the performance of haplotype frequency estimation methods using unrelated individuals, we compared the results of three estimation methods with those from the haplotypes deduced from family pedigrees. To that end we used the HLA phenotypes of the parents of 1040 families as data for the estimation methods and the full pedigree information as data for the deductive method. We evaluated the...
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