Article
Molecular screening of uncoupling protein 2 gene in patients with noninsulin-dependent diabetes mellitus or obesity.
The Journal of clinical endocrinology and metabolism - 1 Aug 1998
Kubota T, Mori H, Tamori Y, Okazawa H, Fukuda T, Miki M, Ito C, Fleury C, Bouillaud F, Kasuga M
Abstract excerpt
Uncoupling protein 2 (UCP2), a member of the family of mitochondrial carrier proteins, has been implicated in the control of whole-body energy balance. The coding region of the human UCP2 gene has now been shown to comprise six exons, and the sequences of the exon-intron boundaries were determine...
Topics
- Adult
- Aged
- Alleles
- Blood Glucose
- Diabetes Mellitus, Type 2
- Female
- Gene Frequency
- Genotype
- Humans
- Ion Channels
- Male
- Membrane Transport Proteins
- Middle Aged
- Mitochondrial Proteins
- Mutagenesis, Site-Directed