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UCP 2 gene polymorphisms in obesity and diabetes, and the role of UCP 2 in cancer

22 Jul 2019

Abstract excerpt

Mitochondria are the primary sites for ATP synthesis and free radical generation in organisms. Abnormal mitochondrial metabolism contributes to many diseases, including obesity, diabetes and cancer. UCP2 is an ion/anion transporter located in mitochondrial inner membrane, and has a crucial role in regulating oxidative stress, cellular metabolism, cell proliferation and cell death. Polymorphisms of the UCP2 gene...

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PMID: 31330574
DOI: 10.1002/1873-3468.13546

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