Article
PTH-C1: a rat continuous cell line expressing the parathyroid phenotype.
Endocrine - 1 Sept 2014
Fabbri Sergio, Ciuffi Simone, Nardone Valeria, Gomes Ana Rita, Mavilia Carmelo, Zonefrati Roberto, Galli Gianna, Luzi Ettore, Tanini Annalisa, Brandi Maria Luisa
Abstract excerpt
The lack of a continuous cell line of epithelial parathyroid cells able to produce parathyroid hormone (PTH) has hampered the studies on in vitro evaluation of the mechanisms involved in the control of parathyroid cell function and proliferation. The PT-r cell line was first established from rat parathyroid tissue in 1987, but these cells were known to express the parathyroid hormone-related peptide (Pthrp) gene,...
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