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Article

The polarized epithelial phenotype is dominant in hybrids between polarized and unpolarized rat thyroid cell lines.

Journal of cell science - 1 Jan 1991

Zurzolo C, Gentile R, Mascia A, Garbi C, Polistina C, Aloj L, Avvedimento V E, Nitsch L

Abstract excerpt

We have studied the expression of cell polarity in hybrids between two rat thyroid epithelial cells: FRT and FRTL-5. FRT cells are polarized but do not express tissue-specific properties, FRTL-5 are unpolarized and express many thyroid-specific genes. A and express many thyroid-specific genes. A...

Topics

Animals
Cell Line
Cell Nucleus
Epithelial Cells
Epithelium
Fluorescent Antibody Technique
Hybrid Cells
Iodine Radioisotopes
Karyotyping
Microscopy, Electron
Phenotype
RNA

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Rats

Thyroglobulin

Thyroid Gland

Transfection

Source

Identifiers

PMID: 1711531
DOI: 10.1242/jcs.98.1.65

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1711531-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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