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Article

Hippocampal volumes in cognitively normal persons at genetic risk for Alzheimer's disease.

Annals of neurology - 1 Aug 1998

Reiman E M, Uecker A, Caselli R J, Lewis S, Bandy D, de Leon M J, De Santi S, Convit A, Osborne D, Weaver A, Thibodeau S N

Abstract excerpt

Brain imaging techniques have the potential to characterize neurobiological changes that precede the onset of cognitive impairment in persons at risk for Alzheimer's disease. As previously described, positron emission tomography (PET) was used to compare 11 cognitively normal persons 50 to 62 years of age who were homozygous for the epsilon4 allele of apolipoprotein E and 22 persons without the epsilon4 allele...

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Identifiers

PMID: 9708558
DOI: 10.1002/ana.410440226

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Preclinical memory decline in cognitively normal apolipoprotein E-epsilon4 homozygotes.Semantic proximity Read ↗

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