Article
Hippocampal volumes in cognitively normal persons at genetic risk for Alzheimer's disease.
Annals of neurology - 1 Aug 1998
Reiman E M, Uecker A, Caselli R J, Lewis S, Bandy D, de Leon M J, De Santi S, Convit A, Osborne D, Weaver A, Thibodeau S N
Abstract excerpt
Brain imaging techniques have the potential to characterize neurobiological changes that precede the onset of cognitive impairment in persons at risk for Alzheimer's disease. As previously described, positron emission tomography (PET) was used to compare 11 cognitively normal persons 50 to 62 yea...
Topics
- Aged
- Alleles
- Alzheimer Disease
- Apolipoproteins E
- Carrier State
- Chi-Square Distribution
- Functional Laterality
- Genotype
- Hippocampus
- Humans
- Logistic Models
- Magnetic Resonance Imaging
- Middle Aged
- Neuropsychological Tests
- Reference Values