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Article

Linking Brain Imaging and Genomics in the Study of Alzheimer's Disease and Aging

1 Feb 2007

Abstract excerpt

My colleagues and I have been using positron emission tomography (PET) and magnetic resonance imaging (MRI) to detect and track the brain changes associated with Alzheimer's disease (AD) and normal brain aging in cognitively normal persons with two copies, one copy, and no copies of the apolipoprotein E (APOE) epsilon4 allele, a common AD susceptibility gene. In this review article, I consider how brain imaging...

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PMID: 17413015
DOI: 10.1196/annals.1379.011

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