Article
Mutation screening of the 5-hydroxytryptamine7 receptor gene among Finnish alcoholics and controls.
Psychiatry research - 27 Feb 1998
Pesonen U, Koulu M, Bergen A, Eggert M, Naukkarinen H, Virkkunen M, Linnoila M, Goldman D
Abstract excerpt
Impaired central serotonin neurotransmission has been associated with increased aggression, impaired impulse control and diurnal activity rhythm disturbances among humans. Neuroanatomic distribution and pharmacological properties of the serotonin 5-HT7 receptor suggest that it may play a role in...
Topics
- Adult
- Alcoholism
- Alleles
- Amino Acid Substitution
- DNA Mutational Analysis
- Female
- Finland
- Gene Frequency
- Genetic Testing
- Genotype
- Humans
- Male
- Middle Aged
- Point Mutation
- Polymorphism, Genetic
- Receptors, Serotonin