Article
Association between HTR7 genetic polymorphisms and alcohol dependence, using the alcohol use disorders identification test (AUDIT).
Alcoholism, clinical and experimental research - 1 Sept 2014
Kim Jeong-Hyun, Park Byung-Lae, Cheong Hyun Sub, Bae Joon Seol, Kim Lyoung Hyo, Kim Jee Wook, Lee Byoung Chul, Seo Cheong Hoon, Kang Tae-Cheon, Park Sun-Hee, Choi Ihn-Geun, Shin Hyoung Doo
Abstract excerpt
BACKGROUND: A recent genome-wide association study has identified 5-hydroxytrytamine (serotonin) receptor 7, adenylate cyclase-coupled (HTR7) as a risk gene for alcohol dependence. In addition, the serotonergic system has been considered as a modulator that plays an important role in alcohol use disorders. Functional, pharmacological, and genetic studies of serotonin neurotransmission have revealed that serotonin...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
